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Scale-able Document management portal for data spread across divisions , business units , Product Families. in Sharepoint 2010

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Hi , 

I have to create a portal to manage documents for medical device manufacturer. There are various divisions under which there are many Business units and business units contains the Product Families.

10-15 Divisions

Each Divisions 5 Business Unites

10-40 Product Family in each division , which contains Document Sets.

The database is expected to grow at 75 GB per year. Documents as many as 75 GB total will be uploaded.

I want to implement document expiration to manage the data so that the inactive data is migrated to other site so that the performance is improved.

My thoughts So far..

I should make sub-sites for  Divisions ( or should i create document libraries for each division) .

Then Lists based on business units and then folder structure inside the lists for Product family.

How could I utilize record center in this project for these requirements.


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